P38.13 Cytology-Histology Concordance for Diagnosis, Histological Subtyping and Molecular Profiling of Lung Cancer

نویسندگان

چکیده

Cytological samples are often the only diagnostic material available for confirmation of lung cancer (LC) diagnosis. The aim present study was to evaluate cytology-histology concordance diagnosis, histological subtyping and molecular profiling LC, determine factors which may affect sample adequacy or concordance. 118 patients with histologically cytologically confirmed LC were retrospectively studied. Clinicopathological features correlated type biological obtained (histological cytological) sampling methods used. Concordance between cytological diagnosis also above parameters. majority male (58.5%), positive smoking history (82.2%), non-small cell subtype tumor (72%) και advanced disease stage (66.9%). Histological adequate evaluation in 94/100 (94%) 85/88 cases (96.6%), respectively malignancy 87/100 (87%) 57/88 (64.8%), respectively. Cytology-histology regard 52.9%. In subgroup, high (96.9%) observed tumor. Molecular testing performed 30/118 (25.4%), most commonly using (23/30, 76.7%); 28/30 these (93.3%) evaluation. a small (p=0.047) univariate but not multivariate analysis. among high, despite relatively low overall No independent correlation any clinicopathological parameters evaluated presence inadequate discordance.

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ژورنال

عنوان ژورنال: Journal of Thoracic Oncology

سال: 2021

ISSN: ['1556-0864', '1556-1380']

DOI: https://doi.org/10.1016/j.jtho.2021.01.794